Alzheimer’s disease continues to be a complex disorder and despite its high prevalence, there is no cure. Moreover, current diagnostic techniques are not helpful for early diagnosis of the disease and consequently disable people from getting the right treatment.
However, new data reveals that Alzheimer's disease indicators could be seen in the blood up to 20 years before symptoms materialise. A group of Australian researchers has created a quick, inexpensive, and non-invasive blood test that may be used to forecast a person's likelihood of acquiring Alzheimer's disease up to 20 years before symptoms appear.
The Australian National University (ANU) researchers have developed a way to use nanotechnology, combined with artificial intelligence (AI), to analyse proteins in the blood to search for signs of early neurodegeneration.
The team developed an ultra-thin silicon chip containing “nanopores” that analyse the proteins one at a time with help from an advanced AI algorithm.
In this method, a tiny sample of blood is placed on a silicon chip and put into a small, portable device the size of a phone that utilises an AI algorithm to look for signatures associated with proteins that exhibit early-onset Alzheimer's symptoms. The journal Small Methods published the findings. The fact that the same test can be used to simultaneously screen for different neurological disorders like Parkinson's disease, multiple sclerosis, and amyotrophic lateral sclerosis is notable.